Seminar on 'Quantitative Label-free Metabolic Imaging of Skin Wound Healing' on Friday

Kyle Quinn, assistant professor of biomedical engineering.
University Relations

Kyle Quinn, assistant professor of biomedical engineering.

Kyle Quinn of the University of Arkansas will give a seminar titled "Quantitative label-free metabolic imaging of skin wound healing."

The seminar will take place at 4 p.m. Friday, March 13, in the Chemistry Building in room 144. There will be refreshments provided prior to the seminar in room 133 starting at 3:45 p.m. The talk is free and open to the public.

Quinn is an assistant professor in the Department of Biomedical Engineering. His research interests are in developing and utilizing non-invasive label-free multiphoton microscopy techniques to characterize the spatiotemporal patterns of disease transgression and tissue repair processes. His research group is currently focused on using two-photon excited fluorescence from the metabolic cofactors (NADH and FAD), collagen second harmonic generation (SHG), fluorescence lifetime imaging (FLIM), and coherent anti-Stokes Raman spectroscopy (CARS) to establish quantitative optical biomarkers for a variety of diseases and conditions.

During the seminar, Quinn will speak on the challenges of diagnosing and treating non-healing wounds, such as diabetic foot ulcers. Non-healing wounds are difficult to diagnose and treat due to their numerous etiologies and the variable efficacy of wound care products. There is a critical need to develop new diagnostic technologies and quantitative biomarkers that are sensitive to specific wound characteristics. Multiphoton microscopy techniques are well-suited for 3D skin imaging and are capable of non-invasively detecting autofluorescence from metabolic cofactors (NADH and FAD) without the need for exogenous dyes.

Quinn will speak about the potential of label-free autofluorescence imaging to distinguish different underlying causes for delays in healing, which may be used in the future to provide patient-specific treatment strategies in the clinic.

Contacts

Megan Parette, communications assistant
Department of Chemistry and Biochemistry
479-575-4601, mbparett@uark.edu

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