The Arkansas Integrative Metabolic Research Center (AIMRC) will host Dr. Patience Okoto, manager of the AIMRC Bioenergetics Core at the U of A, at 12:55 p.m. on Wednesday, April 22, in CHEM 0144. Dr. Okoto will introduce researchers to LC-MS/QTOF metabolomics and share how the Bioenergetics Core can assist investigators in generating impactful metabolic data to advance research.
Abstract: Metabolomics has emerged as a powerful tool for characterizing biochemical processes by enabling comprehensive profiling of small-molecule metabolites in biological systems. Because metabolites represent the downstream products of gene expression and enzymatic activity, metabolomic analyses provide a functional readout of cellular physiology and biochemical pathway activity across diverse biological or experimental conditions. High-resolution mass spectrometry platforms, such as the AIMRC's LC-MS QTOF Mass Spectrometer, enable sensitive and accurate detection of a wide range of metabolites, making them valuable tools for studying metabolic pathways, disease mechanisms and responses to environmental or experimental perturbations. The goal of this seminar is to introduce researchers to the capabilities of LC-MS/QTOF metabolomics and demonstrate how the Bioenergetics Core can support investigators in generating high quality metabolic data to advance research.
Biography: Dr. Patience S. Okoto is the core manager of the Bioenergetics Core at the Arkansas Integrative Metabolic Research Center (AIMRC), where she oversees advanced metabolic phenotyping technologies used to study cellular and whole-organism energy metabolism. She manages and supports the use of multiple metabolic analysis platforms, including Seahorse XF analyzers, Oroboros O2K, Promethion metabolic cages and the Drosophila metabolic screening system. Dr. Okoto earned her Ph.D. in cell and molecular biology from the U of A and holds a B.S. in molecular biology and biotechnology from the University of Cape Coast.
This event is supported by NIGMS of the National Institutes of Health under award number P20GM139768. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
Pizza and beverages will be served. Please contact Kimberley Fuller, fullerk@uark.edu, for more information.
For those unable to attend in person, this seminar will also be available via Zoom.
Topics
Contacts
Kimberley Fuller, AIMRC managing director
Biomedical Engineering
(479) 575-2333, fullerk@uark.edu