Jiali Li, professor of physics, will give a seminar titled "Estimating the shape and conformation of single protein molecules by a solid-state nanopore device" in CHEM 144 from 3:30-4:30 p.m. on Friday, April 14.

There will be refreshments available before the seminar starting at 3:10 p.m. in CHEM 105. The talk is free and open to the public. The seminar will also be available via Zoom for those who would like to attend remotely.

This seminar will present that ionic current measurements through electrolyte-filled nanopores can characterize single protein molecules in an aqueous environment. Li's group shows a solid-state nanopore sensing system can determine the approximate shape, volume, charge, dipole moment and conformation change of individual proteins. These parameters can be used to identify, characterize and quantify proteins and protein complexes with potential implications for structural biology, proteomics, biomarker detection and routine protein analysis.

Li received an M.S. in solid-state physics from the University of Science and Technology of China. She received a Ph.D. in physics/biophysics from City University of New York. Li is a professor of physics at the U of A. She also teaches in the Cell and Molecular Biology Program and the Materials Science and Engineering Program.

Her research interests are in the areas of nanoscale materials characterization and their applications in biophysics that include solid-state nanopore fabrication, single molecules of DNA and protein manipulation, detection and characterization.

Zoom meeting ID: 835 9661 3040
Passcode: 1AnylSem!